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The route from Luton to Southampton is served daily by 93 bus departing from the stations of Luton Town, London Luton Airport, Luton Challney Near Travelodge, Luton, Challney (near Simpson Close) Bus Stop and arriving to the stations of Southampton University Of Southampton, Southampton Coach Station, University Of Southampton.
The average duration of the journey is 4 h 50 min. The first bus leaves at 03:25. The last is at 23:55.

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