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The route from Cologne to Prague is served daily by 28 bus departing from the stations of Cologne / Bonn Airport Busterminal, Cologne South, Airport, Cologne North, Leverkusen, Cologne/Bonn Airport Terminal 2, Cologne East, Refrath and arriving to the stations of Prague Florenc Central Bus Station, Prague ,Hradčanská, Prague ÚAN Florenc, Prague Anděl, Prague Main Railway Station, Prague Wilsonova Bus Station.
The average duration of the journey is 12 h 26 min. The first bus leaves at 02:45. The last is at 20:00.

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