With such a long journey, we would like to give you some advice: you can look for a flight to Prague, or if your budget is limited, you can check night buses and trains to save the daytime for your visits.
When do the first and last buses from Cologne to Prague leave?
While the first bus leaves at :fristDeparture, the last one leaves Cologne at 20:11. The duration of the journey is on average 10 hours and 25 minutes, but it can take you only 9 hours and 45 minutes with the fastest connections.
Which bus companies serve the route Cologne - Prague?
You can travel by bus from Cologne to Prague with Eurolines SA, FlixBus and RegioJet.
Flixbus is undoubtedly one of the youngest and most famous bus companies in whole Europe. With more than 40 millions passengers only in 2017, Flixbus offers national and international bus connections, also with night buses.
Eurolines is one of the leader bus companies in Europe, with more than 350 connections in 23 countries. Among its services you can also find long-distance night buses.