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The route from Birmingham to Manchester is served daily by 121 bus departing from the stations of Birmingham Bearwood, BHM Airport, Birmingham Airport Bus Station, Birmingham Coach Station, Coach Station, Birmingham Five Ways, Great Barr, Birmingham Great Barr and arriving to the stations of Manchester Central Bus Station, Manchester Airport Bus Station, Manchester Coach Station, Manchester Miles Platting.
The average duration of the journey is 3 h 7 min. The first bus leaves at 00:20. The last is at 23:55.

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