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The route from Southampton to Manchester is served daily by 79 trains leaving from from the station of Southampton Central [ SOU ] and arriving at in the stations of Manchester Airport [ MIA ], Manchester Oxford Road [ MCO ], Manchester Piccadilly [ MAN ], Manchester Victoria [ MCV ].
The average journey duration is 5 h 17 min. The first train leaves at 04:42. The last one is at 23:44.

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