If the offers provided by buses do not suit your needs, trains and carpooling could represent a good alternative for this distance.
What time do the busses to Nijmegen leave?
To get from Rotterdam to Nijmegen by bus it will take you 4 hours and 35 minutes. The first departure is scheduled at 18:03, while the last bus is at 18:03.
Which bus companies serve the route Rotterdam - Nijmegen?
Virail counts among its partners also FlixBus, with buses from Rotterdam to Nijmegen.
Flixbus is undoubtedly one of the youngest and most famous bus companies in whole Europe. With more than 40 millions passengers only in 2017, Flixbus offers national and international bus connections, also with night buses.