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The route from Milton Keynes to Southampton is served daily by 60 bus departing from the stations of Milton Keynes Coachway, Milton Keynes Town Center, Nottingham and arriving to the stations of SOUTHAMPTON (Coach Station), Southampton University Of Southampton, Southampton Coach Station.
The average duration of the journey is 5 h 15 min. The first bus leaves at 03:30. The last is at 21:25.

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