If the offers provided by buses do not suit your needs, trains and carpooling could represent a good alternative for this distance.
When are the buses of the line Mainz - Cologne scheduled?
The first bus leaves from Mainz at 18:04, while the last one leaves at 18:04. The journey takes 3 hours and 10 minutess.
Which bus companies are in service in the route Mainz - Cologne?
Among the several partners of virail, you can also find FlixBus, offering buses from Mainz to Cologne.
Flixbus is undoubtedly one of the youngest and most famous bus companies in whole Europe. With more than 40 millions passengers only in 2017, Flixbus offers national and international bus connections, also with night buses.