If the offers provided by buses do not suit your needs, trains and carpooling could represent a good alternative for this distance.
Since the journey from Frankfurt to Berlin is not so long, the bus is a good solution, but if you are looking for more offers or departure times, you can also have a look at trains and carpooling solutions.
When are the buses of the line Frankfurt - Berlin scheduled?
While the first bus leaves at 01:07, the last one leaves Frankfurt at 15:07. The duration of the journey is on average 9 hours and 45 minutes, but it can take you only 6 hours and 45 minutes with the fastest connections.
Which bus companies serve the route Frankfurt - Berlin?
Virail counts among its partners also FlixBus, Eurolines Germany and DeinBus, with buses from Frankfurt to Berlin.
Flixbus is undoubtedly one of the youngest and most famous bus companies in whole Europe. With more than 40 millions passengers only in 2017, Flixbus offers national and international bus connections, also with night buses.