For such long distances, travelling by bus could not be the best solution. Check out alternatives by plane: with some luck, you will find low-cost tickets from Brindisi to Genoa and be a lot faster!
When are the buses of the line Brindisi - Genoa scheduled?
The first bus to Genoa leaves at 07:08, while the last one is scheduled at 23:08. The journey takes on average 15 hours and 55 minutes, but the fastest connections take only 14 hours and 5 minutes.
Which companies can you travel with from Brindisi to Genoa?
You can travel by bus from Brindisi to Genoa with FlixBus and Marino.
Flixbus is undoubtedly one of the youngest and most famous bus companies in whole Europe. With more than 40 millions passengers only in 2017, Flixbus offers national and international bus connections, also with night buses.
Marino is an Italian company mostly active in Southern Italy, but providing bus connections driving up to Northern Italy and also to France, Switzerland and Germany.