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The route from Barcelona to Brussels is served daily by 44 bus departing from the stations of Barcelona Sants Central Bus Station, Barcelona Bus Station North, Barcelona Sants, Barcelona Nord and arriving to the stations of Brussels North Train Station, Brussels Midi / Brussel Zuid East, Gare Du Nord, Brussels North Station.
The average duration of the journey is 23 h 45 min. The first bus leaves at 01:35. The last is at 21:30.

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